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Changes in serum levels of interleukin 4 and malondialdehyde (MDA) following 8 weeks of aquatic aerobic training in breast cancer survivors | ||
| New Approaches in Exercise Physiology | ||
| مقاله 9، دوره 8، شماره 15، شهریور 2026 | ||
| نوع مقاله: Research Paper | ||
| شناسه دیجیتال (DOI): 10.22054/nass.2025.90179.1218 | ||
| نویسندگان | ||
| Zahra Sayevand* 1؛ Marziyeh Maleki2؛ Mahdiyeh Khosravi3 | ||
| 1Department of Physical Education, Mal.C., Islamic Azad University, Malayer, Iran | ||
| 2Department of Sports Sciences, Faculty of human Sciences, Malayer University, Malayer, Iran. | ||
| 3Department of Exercise Physiology, Faculty of Physical Education and Sport Science, Razi University, Kermanshah, Iran | ||
| چکیده | ||
| Objective: Breast cancer is one of the most common cancers affecting women worldwide, with survivors often experiencing long-term side effects such as chronic inflammation and oxidative stress. The objective of this study was to investigate the effects of an 8-week aquatic aerobic training program on serum levels of interleukin-4 (IL-4) and malondialdehyde (MDA) in breast cancer survivors. Methods: This quasi-experimental study involved 20 breast cancer survivors who were randomly assigned to either an experimental group (n = 10) that underwent aquatic aerobic exercise or a control group (n = 10) that received no intervention. Pre- and post-test measurements of IL-4 and MDA levels were taken to assess the impact of the exercise intervention. The aquatic aerobic training program lasted 8 weeks, with sessions held three times per week. Serum levels of IL-4 and MDA were measured using enzyme-linked immunosorbent assays (ELISA). Results: The results revealed a significant reduction in IL-4 levels in the experimental group (p = 0.001), while no significant change was observed in the control group (p = 0.861). Similarly, MDA levels were significantly reduced in the experimental group (p = 0.001), while the control group showed no significant change (p = 0.659). These findings suggest that aquatic aerobic exercise may reduce inflammation and oxidative stress in breast cancer survivors. Conclusion: In conclusion, aquatic aerobic exercise appears to be a beneficial intervention for improving inflammatory and oxidative biomarkers in breast cancer survivors, potentially contributing to better long-term health outcomes. | ||
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