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siahkouhian, marefat, Abdoli, Mohammad, Kolivand, Hanieh. (1404). The effect of 8 weeks of swimming exercise on serum levels of Visfatin, TNF-α and insulin resistance in obese women with type 2 diabetes. سامانه مدیریت نشریات علمی, 7(13), -. doi: 10.22054/nass.2025.90138.1214
marefat siahkouhian; Mohammad Abdoli; Hanieh Kolivand. "The effect of 8 weeks of swimming exercise on serum levels of Visfatin, TNF-α and insulin resistance in obese women with type 2 diabetes". سامانه مدیریت نشریات علمی, 7, 13, 1404, -. doi: 10.22054/nass.2025.90138.1214
siahkouhian, marefat, Abdoli, Mohammad, Kolivand, Hanieh. (1404). 'The effect of 8 weeks of swimming exercise on serum levels of Visfatin, TNF-α and insulin resistance in obese women with type 2 diabetes', سامانه مدیریت نشریات علمی, 7(13), pp. -. doi: 10.22054/nass.2025.90138.1214
siahkouhian, marefat, Abdoli, Mohammad, Kolivand, Hanieh. The effect of 8 weeks of swimming exercise on serum levels of Visfatin, TNF-α and insulin resistance in obese women with type 2 diabetes. سامانه مدیریت نشریات علمی, 1404; 7(13): -. doi: 10.22054/nass.2025.90138.1214

The effect of 8 weeks of swimming exercise on serum levels of Visfatin, TNF-α and insulin resistance in obese women with type 2 diabetes

New Approaches in Exercise Physiology
دوره 7، شماره 13، شهریور 2025
نوع مقاله: Research Paper
شناسه دیجیتال (DOI): 10.22054/nass.2025.90138.1214
نویسندگان
marefat siahkouhian* 1؛ Mohammad Abdoli2؛ Hanieh Kolivand3
1Professor of Exercise Physiology, Department of Exercise Physiology, Department of Exercise Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.
2Department of Sports Management, Faculty of Physical Education and Sport Sciences, Arak University, Arak, Iran.
3Department of Pathology and Corrective Movements, Faculty of Physical Education and Sport Sciences, Allameh Tabatabaei University, Tehran, Iran
چکیده
Objective:
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder often associated with obesity, inflammation, and insulin resistance.

Methods:
Thirty obese women with T2DM (mean age 44.6 ± 5.1 years) participated voluntarily and were randomly assigned into experimental (n = 15) and control (n = 15) groups. The experimental group performed swimming training three sessions per week for eight weeks at an intensity of 60–85% of maximum heart rate, while the control group maintained their routine lifestyle. Blood samples were collected 24 hours before and 48 hours after the intervention to determine serum visfatin, plasma TNF-α, fasting glucose, and insulin levels. Data were analyzed using paired and independent t-tests and ANCOVA (p < 0.05).

Results:
Swimming training significantly decreased serum visfatin (from 28.6 ± 4.3 ng/mL to 22.3 ± 3.5 ng/mL; p = 0.001), plasma TNF-α (from 11.2 ± 1.8 pg/mL to 8.6 ± 1.5 pg/mL; p = 0.002), and HOMA-IR index (from 5.12 ± 0.98 to 3.72 ± 0.74; p = 0.001) in the experimental group. No significant changes were observed in the control group (p > 0.05).

Conclusion:
Eight weeks of moderate-intensity swimming exercise effectively reduced inflammatory markers and improved insulin sensitivity in obese women with type 2 diabetes. These results suggest that aquatic aerobic training can be recommended as a safe, practical, and efficient therapeutic approach for managing metabolic and inflammatory complications in diabetic patients.
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تعداد مشاهده مقاله: 39


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